Refrigerant Replacement Guide
Looking to replace refrigerant in your appliance or system? Our comprehensive Refrigerant Replacement Guide provides you with all the information you need to safely and effectively change your refrigerant. This guide covers the various types of refrigerants available, including their properties and compatibility with different systems. We also walk you through the step-by-step process of replacing refrigerant, highlighting important safety precautions and considerations. Whether you are a professional HVAC technician or a DIY enthusiast, our Refrigerant Replacement Guide is your go-to resource for ensuring proper refrigerant replacement. Follow this guide to maintain the efficiency and longevity of your cooling system.
RefrigerantInc.com — Wholesale Supply
Refrigerant
Replacement
Guide
Find the exact non-flammable, low-GWP drop-in replacement for your R-22, R-404A, R-410A, and more. Search by your current refrigerant below.
Step 1 — Search or select your current refrigerant
Why switch now?
EPA AIM Act regulations are phasing down high-GWP HFCs through 2025–2036. Refrigerants like R-404A (GWP 3,922) and R-22 face tightening supply and rising prices. Switching to a low-GWP non-flammable alternative now protects your equipment investment and keeps systems compliant.
All RS-series refrigerants are A1 rated (non-toxic, non-flammable) and designed as direct drop-in replacements — no oil change or major system retrofit required in most applications. Always verify with your equipment manufacturer.
Questions? Call 888-593-7366 or contact our team — we can match the right refrigerant to your specific system.