Refrigerant Replacement Guide

RefrigerantInc.com — Wholesale Supply

Refrigerant
Replacement
Guide

Find the exact non-flammable, low-GWP drop-in replacement for your R-22, R-404A, R-410A, and more. Search by your current refrigerant below.

Non-flammable Low GWP No oil change required Drop-in compatible

Step 1 — Search or select your current refrigerant

Why switch now?

EPA AIM Act regulations are phasing down high-GWP HFCs through 2025–2036. Refrigerants like R-404A (GWP 3,922) and R-22 face tightening supply and rising prices. Switching to a low-GWP non-flammable alternative now protects your equipment investment and keeps systems compliant.

All RS-series refrigerants are A1 rated (non-toxic, non-flammable) and designed as direct drop-in replacements — no oil change or major system retrofit required in most applications. Always verify with your equipment manufacturer.

Questions? Call 888-593-7366 or contact our team — we can match the right refrigerant to your specific system.