Buy R422D Refrigerant | R22 Retrofit Replacement | Free Shipping — Refrigerant Inc

R422D Refrigerant — R22 Retrofit Replacement, Free Nationwide Shipping

R-422D is an HFC blend refrigerant used as a retrofit replacement for R22 in existing residential and commercial air conditioning and heat pump systems. Sold under the brand name ISCEON MO29 by Chemours (formerly DuPont), R422D has a long track record in the U.S. market as a practical R22 service alternative, particularly in older commercial AC equipment. Refrigerant Inc stocks genuine, virgin R422D with free shipping to all 48 continental states.

What Systems Use R422D?

R422D is used as a retrofit refrigerant in existing R22 air conditioning and heat pump systems including:

• Residential split system air conditioners and heat pumps installed before 2010
• Light commercial packaged units and split systems originally charged with R22
• Older commercial rooftop units running R22
• Close-control and precision AC systems originally designed for R22

R422D is not used in new equipment — it is a service refrigerant for the existing R22 installed base.

R422D (ISCEON MO29) — Technical Overview

R422D is a blend of R125, R134a, and R600a (isobutane). The small percentage of isobutane improves lubricity and oil return in existing R22 systems, which helps compensate for the reduced miscibility of HFC refrigerants with the mineral and alkylbenzene oils typically found in R22 equipment. Key properties:

• Operating pressures — R422D operates at pressures reasonably close to R22, making it compatible with most existing R22 system components without hardware replacement
• Oil compatibility — The isobutane component improves compatibility with mineral and alkylbenzene oil already in R22 systems, reducing the urgency of an oil change compared to some other R22 alternatives
• Non-flammable (A1) — Despite containing a small amount of isobutane, R422D meets the ASHRAE A1 non-flammable classification as formulated
• No ozone depletion — Contains no chlorine, zero ODP

R422D vs. Other R22 Replacements

Several refrigerants compete in the R22 retrofit market. Here's how R422D compares to the most common alternatives we carry:

• R422D (ISCEON MO29) — Established Chemours product with long commercial track record; isobutane component aids oil return; well-suited for older commercial equipment
• R438A (MO99) — Generally considered the closest pressure and capacity match to R22; most widely used R22 retrofit in the U.S.
• RS-44b (R453A) — Closest overall thermodynamic match to R22; minimal oil change required
• R422B — Similar HFC blend to R422D with slightly different composition; another established commercial retrofit option
• R22 — Still the best-performing option for original R22 system performance when cost is not a constraint

Not sure which R22 replacement is right for your system? Call us at 888-593-7366 — we can help you choose based on equipment type and application.

R422D Retrofit Procedure

1. Recover all existing R22 from the system using an EPA-certified recovery machine
2. Check for and repair any leaks
3. Pull a deep vacuum (500 microns or lower)
4. Charge with R422D as a liquid to the manufacturer's recommended weight — typically close to the original R22 charge weight
5. Verify operating pressures against R422D PT charts and check superheat/subcooling
6. Label the system with new refrigerant type, charge weight, and conversion date

A POE oil change is recommended for long-term compressor health but is generally not required for the system to operate, thanks to R422D's isobutane component improving oil miscibility.

Why Buy R422D From Refrigerant Inc

• Virgin, Factory-Sealed Product — Genuine R422D, never reclaimed or gray market.
• Free Shipping to All 48 States — No freight fees added at checkout.
• Same or Next-Day Processing — Orders placed before 2PM EST ship the same day.
• Contractor & Wholesale Pricing — Volume accounts available. Call 888-593-7366.

Shipping Information

R422D ships via ground freight to all 48 continental states. Alaska and Hawaii excluded. Most orders ship within 1 business day. Transit time is typically 2–5 business days depending on location.

Frequently Asked Questions

Is R422D the same as ISCEON MO29?
Yes. ISCEON MO29 is Chemours' brand name for R422D. They are the same refrigerant — MO29 is simply the trademarked product name used in Chemours' ISCEON line.

What is R422D made of?
R422D is a blend of R125, R134a, and a small amount of R600a (isobutane). The isobutane component improves lubricity and oil return characteristics, helping the refrigerant work more effectively with the mineral and alkylbenzene oils in existing R22 systems.

Is R422D flammable?
No. Despite containing a small percentage of isobutane (which is flammable on its own), R422D as formulated meets the ASHRAE A1 non-flammable classification. Standard refrigerant service equipment is compatible.

Do I need to change the oil when converting to R422D?
A POE oil change is recommended for long-term compressor life but is generally not required for the system to run on R422D. The isobutane component helps with oil return in systems still running mineral or alkylbenzene oil, which is one of R422D's advantages in older commercial equipment.

How does R422D compare to MO99 (R438A)?
Both are solid R22 retrofit options. R438A (MO99) is generally considered to have a closer pressure and capacity match to R22 and is more widely used in the U.S. residential market. R422D (ISCEON MO29) has a longer commercial track record, particularly in older commercial equipment, and its isobutane component provides an oil return advantage. Either is a viable choice depending on contractor preference and equipment type.

Can I mix R422D with leftover R22 in the system?
No. Always fully recover the existing R22 charge before introducing R422D. Mixing creates an unidentifiable refrigerant blend that cannot be properly serviced or recovered.